IJEP 44(13): 1209-1215 : Vol. 44 Issue. 13 (Conference 2024)
1. Graphic Era (Deemed to be University), Department of Biotechnology, Dehradun – 248 001, Uttarakhand, India
2. Graphic Era (Deemed to be University), Department of Microbiology, Dehradun – 248 001, Uttarakhand, India
3. Uttarakhand State Council for Science and Technology (UCOST), Dehradun, Uttarakhand, India
4. Graphic Era Hill University, Research and Development Cell, Dehradun – 248 001, Uttarakhand, India
Abstract
Schrebera swietenioides Roxb., a member of the Oleaceae family, is distributed in various geographical regions, such as Peru, Tropical and Southern Africa, India and Southeast Asia. The primary objective of the present review was to collect the most recent data on the field of botany, ethnopharmacology, phytochemistry and the potential pharmacological action of S. swietenioides, thereby presenting exciting opportunities for the advancement of innovative adjuvant natural therapies. Phytochemical exploration of S. swietenioides has resulted in the identification and extraction of an array of bioactive compounds, including steroids, triterpenoids, carbohydrates, flavonoids, saponins and phenols. Moreover, previous investigations have provided evidence that plant extracts and isolated constituents derived from S. swietenioides possess significant pharmacological properties. Furthermore, it has been documented that S. swietenioides exhibits a diverse range of pharmacological effects, such as antibacterial, anti-inflammatory, hepatoprotective, antioxidant, antidiabetic, antipyretic and wound-healing properties. A comprehensive exploration of scientific databases, such as Google Scholar, Scopus, Science Direct, Springer, Wiley and PubMed, was carried out in order to conduct a complete literature search on S. swietenioides. The findings of the relevant studies were thoroughly examined and the key data derived from these studies were summarized in the present review. In the future, it would be beneficial to conduct additional in-vitro and in-vivo therapeutic studies in order to uncover novel modes of action, explore pharmacodynamics and develop new pharmaceutical compositions for the intended target.
Keywords
Extract, Phytochemicals, Biological applications, Medicinal plant
References
- Ghorbani, A. 2014. Clinical and experimental studies on polyherbal formulations for diabetes: Current status and future prospective. J. Integrative Medicine. 12: 336-345.
- Patwardhan, B., et al. 2005. Ayurveda and traditional Chinese medicine: A comparative overview. Evidence Based Complementary Alternative Medicine. 2: 465-473.
- Hsu, E. and R. Barrett. 2008. Traditional Asian medical systems. In International encyclopedia of public health. Academic Press. pp 349-357.
- Duke, J.A. 2002. Handbook of medicinal herbs. CRC Press.
- Yuan, H., et al. 2016. The traditional medicine and modern medicine from natural products. Molecules. 21: 559.
- Fridlender, M., Y. Kapulnik and H. Koltai. 2015. Plant derived substances with anti-cancer activity: From folklore to practice. Frontiers Plant Sci., 6: 799.
- Saggar, S., et al. 2022. Traditional and herbal medicines: Opportunities and challenges. Pharmacognosy Res., 14: 107-114.
- Gurib-Fakim, A. 2006. Medicinal plants: Traditions of yesterday and drugs of tomorrow. Molecular Aspects Medicine. 27: 1-93.
- Rout, J., A.L. Sajem and M. Nath. 2012. Medicinal plants of north Cachar hills district of Assam used by the Dimasa tribe. Indian J. Traditional Knowledge. 11(3).
- Parasuraman, S. 2018. Herbal drug discovery: Challenges and perspectives. Curr. Pharmacoga-nomics Personalized Medicine. 16: 63-68.
- Malla, B., D.P. Gauchan and R.B. Chhetri. 2015. An ethno-botanical study of medicinal plants used by ethnic people in Parbat district of western Nepal. J. Ethnopharmacol., 165: 103-117.
- Maroyi, A. 2013. Traditional use of medicinal plants in south-central Zimbabwe: Review and perspectives. J. Pathonobiol. Ethnomedicine. 9: 1-18.
- Akhtar, N., et al. 2021. ISSR-based genetic diversity assessment of Genus Jasminum L. (Oleaceae) from Pakistan. Plants. 10: 1270.
- Devi, V.A. and K. Mallikarjuna. 2018. In-vitro antimicrobial and antidiabetic activity of leaf extracts of Schrebera swietenioides and Homalium zeyla-nicum. Int. J. Life Sci. Pharma Res., 6: 1-7.
- Batiha, G.E.S., et al. 2020. The pharmacological activity biochemical properties and pharmacokinetics of the major natural polyphenolic flavonoid: Quercetin. Foods. 9: 374.
- Ganeshpukar, A. and A. K. Saluja. 2017. The pharmacological potential of rutin. Saudi Pharmaceutical J., 25: 149-164.
- Yang, D., et al. 2020. Quercetin: Its main pharmacological activity and potential application in clinical medicine. In Oxidative medicine and cellular longevity. 2020: 8825387.
- Kadereit, J.W. 2004. Flowering plants. Dicotyledons: Lamiales (except Acanthaceae including Avicenniaceae). Springer-Verlag, Berlin and Heidelberg.
- Mahida, Y. and J. Mohan. 2007. Screening of plants for their potential antibacterial activity against Staphylococcus and Salmonella spp. Natural Product Radiance. 6: 301-305.
- Bosser, J. and R. Robevohitra. 1985. The genus Schrebera (Oleaceae) fround in Madagascar. Bulletin Muséum National Histoire Naturelle. 7: 59-66.
- Sasidharan, N. 2006. Illustrated manual on tree flora of Kerala supplemented with computer aided identification. Kerala Forest Research Institute, Paechi, Kerala.
- Shetty, B. and V. Singh. 1967. Flora of Rajasthan. In Flora of India. Botanical Survey of India, Calcutta.
- Tripathi, Y., et al. 1996. Medicinal plants of Rajasthan in Indian system of medicine. Ancient Sci. Life. 15: 190.
- Wagh, V.V. and A.K. Jain. 2015. Inventory of ethnobotanicals and other systemic procedures for regional conservation of medicinal and sacred plants. Env. Systems Decision. 35: 143-156.
- Singh, H. 2012. Traditional phytotherapy for the treatment of hydrocele in Odisha, India. Anc. Sci. Life. 31: 137-140.
- Gamit, S.B. 2018. Traditional knowledge documentation and pharmacological study of selected potential medicinal plants from Tapi district, Gujarat. Department of Chemistry, Gujarat University.
- Padal, S.B.S., et al. 2010. Ethnomedicinal plants from Paderu divison of Visakhapatnam district, A.P., India. J. Phytol., 2(8).
- Tulliballi, S. 2012. Phytochmical and biological studies on Schrebera swietenioides Roxb. Barleria montana wight and Rotula aquatica lour. Department of Pharmacy, Andhra University.
- Jimenez-Garcia, S.N., et al. 2018. Phytochemical and pharmacological properties of secondary metabolities is barries (chapter 13). In Therapeutic foods. Ed A.M. Holban and A.M. Grumezescu. Academic Press. pp 397-427.
- Manda, H., et al. 2009. Antioxidant, anti-inflammatory and antipytetic activities of ethyl acetate fraction of ethanolic extract of Schrebera swiete-nioides Roxb. root. Int. J. Toxicol. Pharmacol. Res., 1: 7-11.
- Kumar, D.L., et al. 2011. Alpha-glucosidase inhibitory activities of Wrightia tinctoria Roxb. and Schrebera swietenoides Roxb. bark extract. Res. J. Pharmacol. Pharmacodynamics. 3: 22-24.
- Tulliballi, S. and G. Seru. 2013. Hepatoprotective and in-vitro antimicrobial activities of phytochemical analysis of Schrebera swietenoides (Roxb.). J. Pharmacy Res., 6: 466-469.
- Niranjan, M., et al. 2010. Antibacterial activity of Schrebera swietenoides Roxb. against some human pathogenic bacteria. J. Pharmacy Res., 3: 1779-1781.
- Sharifi-Rad, M., et al. 2020. Lifestyle, oxidative stress and antioxidants: Back and forth in the pathophysiology of chromic diseases. Frontiers Physiol., 11: 694.
- Chukwuma, I.F., et al. 2023. Phytochemical profiling and antioxidative potential of phenolic-rich extract of Cola acuminata nuts. Biointerface Res. Appl. Chem., 13: 29.
- Goyal, P., et al. 2020. Evaluation of in-vitro antioxidant effect of Schrebera swietenoides leaf aquous extract. J. Pharmaceutical Sci. Innovation. 9: 60-62.
- Bagali, R.S. and S.S. Jalapure. 2010. Evaluation of antidiabetic and antioxidant effect of Schrebera swietenoides fruit ethenolic extract. Del. Phar-macia Lettre. 2: 278-288.
- Tulliballi, S. and G. Seru. 2015. Antidiabetic activity on methanolic extracts of Schrebera swiete-noides Roxb. roots in streptozotocin induced diabetic rats. Int. J. Pharmacy Pharmaceutical Sci., 7: 246-248.
- Rasal, A.S., et al. 2009. Evaluation of the healing potential of Schrebera swietenoides in the dexamethasone-suppressed wound healing in rodents. Int. J. Lower Extremity Wounds. 8: 147-152.
- Kumar, N., et al. 2017. Evaluation of hepatopro-tective effect of aqueous of Schrebera swieten-oides bark against carbon tetrachloride-induced toxicity in wister rats. Adv. Sci. Letters. 23: 1917-1920.
- Sharifi-Rad, J., et al. 2023. Santalum genus: Phyto-chemical constituents, biological activities and health promoting effects. Zeitschrift fur Naturfor-schung C. 78: 9-25.
