Roscoea purpurea Smith: A Systematic Exploration of its Geographic Range, Traditional Applications, Phytochemical Profile and Medicinal Properties

IJEP 44(13): 1216-1223 : Vol. 44 Issue. 13 (Conference 2024)

Shivani Negi1, Kshetrimayum Renison1, Rajnesh Bharadwaj2, Avinash Sharma3 and Janhvi M. Rawat1*

1. Graphic Era (Deemed to be University), Department of Biotechnology, Dehradun – 248 002, Uttarakhand, India
2. Graphic Era Hill University, School of Agriculture, Dehradun – 248 002, Uttarakhand, India
3. National Centre for Cell Science, Pune – 411 007, Maharashtra, India

Abstract

Roscoea purpurea Smith., commonly known as Kakoli, is a perennial herbaceous plant of the Zingiberaceae family. It is native to Nepal and abundantly distributed in the Himalayas between altitudes of 1500-3100 m above sea level. Ashtavarga, an important polyherbal Ayurvedic formulation, contains eight plants including Kakoli. Each of them possesses diverse medicinal attributes, like Jeevaniya (rejuvenation), Brhnayiya (growth promotion) and Vayasthapan (anti-aging). The tuberous rhizome of R. purpurea has a long history of traditional use in the treatments of diabetes, diarrhoea, hypertension, fever, immunostimulants, inflammation, excessive thirst and rheumatic pain. These therapeutic properties are linked with a variety of secondary metabolites, such as tannins, saponins, phenolics, flavonoids, alkaloids and glycoside compounds. The bioactive compounds are valuable medicinal resources in the Indian Himalayan region, exhibiting potential applications in both traditional and modern healthcare systems. Several studies have been reported on R. purpurea, including its traditional uses, phytochemistry, genetic diversity, cytotoxicity effects, antioxidant potential and antimicrobial activity. The unregulated harvesting practices and natural disasters have significantly changed the habitat and led to a severe decline in the natural populations. Consequently, R. purpurea is frequently harvested from the wild to meet the rising demand for pharmaceuticals and is categorized as a threatened medicinal plant. Therefore, there is an immediate need to establish conservation strategies for the species. Subsequently, the central focus of this article is directed toward the compilation and evaluation of published data regarding the geographic distribution, traditional applications, phytochemical composition and medicinal properties of R. purpurea.

Keywords

Astavarga, Indian Himalayan region, Kakoli, Phyto-chemicals, Roscoea purpurea Smith, Zingiberaceae

References

  1. Suyal, R., et al. 2020. Status of two threatened Astavarga herbs, Polygenatum cirrhiofolium and Malaxis muscifera in west Himalaya conservation implications. Proc. Natl. Acad. Sci. India B Biol. Sci., 90(3): 695-704.
  2. Singh, J.S. 2006. Sustainable development of the Indian Himalayan region: Linking ecological and economic concerns. Curr. Sci., 90(6): 784-788.
  3. Samant, S.S., et al. 1998. Medicinal plants of Indian Himalaya: Diverstiy distribution potential values. Gyanodaya Prakashan, Nanital.
  4. Kala, C.P., P.P. Dhyani and B.S. Sajwan. 2006. Developing the medicinal plants sector in northern India: Challenges and opportunities. J. Ethnobiol. Ethnomedicine. 2: 1-15.
  5. Virk, J.K., et al. 2015. Lack of pharmacological basis of substitution of an endangered plant group Ashtawarga– A significant ingredient of polyherbal formulations. American J. Phytomed. Clin. Ther., 2: 690-712.
  6. Vij, D., P.K. Srivastava and R.K. Mishra. 2019. Astavarga (group of eight medicinal plants): The wonder herbs of Ayurveda. Int. Ayurvedic Med. J., 7(9): 1564-1571.
  7. Paudel, B.R., et al. 2018. Reproductive isolation in alpine gingers: How to coexisting Roscoea (R. purpurea and R. tumjensis) conserve species integrity? Ecol. Int. J. Org. Ecol., 72(9): 1840-1850.
  8. Devkota, H.P. and D. Timalsina. 2021. Traditional uses, phytochemistry and biological activities of Roscoea purpurea Sm. Ethnobot. Res. Appl., 22: 1-7.
  9. Misra, A., et al. 2015. Nutritional evaluation, antioxidant studies and quantification of polyphenolics in Roscoea purpurea tubers. BMC Res. Note. 8: 1-7.
  10. Joshi, V.K. 1983. Evolution of the concept of Astavarga. Indian J. Hist. Sci., 18(1): 9-14.
  11. Balkrishna, A., et al. 2012. Astavarga plants-threatened medicinal herbs of the north-west Himalaya. Int. J. Med. Arom. Plants. 2(4): 661-676.
  12. Giri, L., et al. 2017. Oxidative DNA damage protective activity and antioxidant potential of Ashtvarga species growing in the Indian Himalayan region. Ind. Crops Prod., 102: 173-179.
  13. Singh, N., et al. 2018. Importance of endangered/rare, Astavarga medicinal plants in traditional system of medicine in ayurveda. Int. J. Agric. Sci., 14(1): 258-265.
  14. Panwar, G.S., S.K. Srivastava and P.L. Uniyal. 2017. Cellus-mediated organogensis in Lilium polyphyllum D. Don ex Royle: A critically endangered Astavarga plant. Curr. Sci., 113(5): 946-951.
  15. Kaur, S. and K.K. Bhutani. 2010. Macropropa-gation of Malaxis acuminata D. Don: A rare orchid of high therapeutic value. J. Medicinal Aromat. Plants. 1(2): 29.
  16. Bisht, S., N.S. Bisht and S. Bhandari. 2012. In-vitro macro-propagation in Polygonatum verticil-latum (L.) All. an important theratened medicinal herb of northen India. Physiol. Mol. Biol. Plants. 18: 89.93.
  17. Giri, L., et al. 2012. In-vitro propagation, genetic and phyto-chemical assessment of Habenaria edgeworthii: An important Astavarga plant. Acta Physiol. Plants. 34: 869-875.
  18. Saha, K., R. K. Sinha and S. Sinha. 2020. Distribution, cytology, genetic diversity and molecular phylogeny of selected species of Zingiberaceae: A review. Feddes Report. 131(1): 58-68.
  19. Mans, D.R., et al. 2019. Phytochemical and pharmacological support for the traditional uses of Zingibe-racea species in Suriname- A review of the literature. Pharmacogn. J., 11: 1511-1525.
  20. Basor, T., B. Thapa and N. Timsina. 2022. Phyto-pharmacological and multi-elemental profiling of potential Zingiberaceae species. J. Phytopharm., 11(5): 360-363.
  21. Li, D.B., et al. 2020. An ecological barrier between the Himalayas and the Hengduan mountains maintains the disjunct distribution of Roscoea. J. Biogeogr., 47(2): 326-341.
  22. Hu, H.S., et al. 2023. Plastid phylogenomics and species discrimination in the Chinese clade of Roscoea (Zingiberaceau). Plant Drivers. 45(5): 523–534.
  23. Dhyani, A., et al. 2021. Ecological features and traditional knowledge of Roscoea alpina Royle a medicinal plant in Himalaya. Indian J. Tradit. Knowl., 20(1): 167-173.
  24. Pandey, B.P. and S.P. Pradhan. 2020. Chemical composition in-vitro antioxidant and enzymes inhibitory potential of three medicinally important plants from Nepal (Lepisorus mehrae, Pleuro-spermum benthamii and Roscoea auriculata). Adv. Tradit. Med., 22(1): 75-90.
  25. Rawat, S., et al. 2016. Antioxidant and anti-microbial properties of some ethno-therapeutically important medicinal plants of Indian Himalayan region. 3 Biotech., 6: 1-12.
  26. Paudel, B.R., et al. 2019. The effect of elevational gradient on alphine giners (Roscoea alpina and R. purpurea) in the Himalaya. Peer. J., 7: e7503.
  27. Vikaspedia. Roscoea purpurea. Available at: https://vikaspedia. in/agriculture/crop-production/package-of-practies/medicinal-and-aromatic-plants/roscoea-purpurea.
  28. Paudel, B.R., et al. 2016. Coevolutionary elaboration of pollunation-related traits in an alpine ginger (Roscoea purpurea) and a tabanid fly in the Nepalese Himalayas. New Phytol., 21(4): 1402-1411.
  29. Singh, G. and G.S. Rawat. 2011. Ethnomedicinal survey of Kedamath wildlife sanctuary in western Himalaya, India. Indian J. Fundam. Appl. Life Sci., 1(1): 35-46.
  30. Rana, J.C., et al. 2004. Cultivation of Hedychium spicatum (Kapoor kachari), Valeriana vallichii and Roscoea purpurea in hill regions of India. Indian For., 130: 1008-1018.
  31. Kumari, P., G.C. Joshi and L.M. Tewan. 2011. Diversity and status of ethno-medicinal plants of Almora district in Uttarakhand, India. Int. J. Biodi-versity Conser., 3 (7): 298-326.
  32. Kaur, G., et al. 2017. Kakoli (Roscoea purpurea)-A wonderful panacea for disorders of reproductive system. Indo American J. Pharm. Sci., 4(11): 3879-3887.
  33. Patil, G.B. 2023. Clinical evaluation of effect of Roscoea purpurea, Curcuma longa and Glycyrrhiza glabara decoction gargle in pharyngitis. J. Popul. Ther. Clin. Pharmacol., 30(17): 908-912.
  34. Rawat, S., et al. 2017. Geographical and environmental variation in chemical constituents and antioxidant properties of Roscoea procera Wall. J. Food Biochem., 41(2): e12302.
  35. Rawat, S., et al. 2018. Influence of the growth phenophases on the phenolic composition and antioxidant properties of Roscoea procera Wall. in western Himalaya. J. Food Sci. Tech., 55: 578-585.
  36. Singamaneni, V., et al. 2021. Coronarin K and L: Two novel labdane diterpenes from Roscoea purpurea: An ayurvedic crude-drug. Frontier Chem., 9: 642073.
  37. Rawat, S.S., et al. 2015. Separation and identification of phytochemicals from Roscoea procera Wall (kakoli), an ingredient of Asthtavarga. Indian J. Agric. Biochem., 28(2): 143-149.
  38. Srivastava, S., et al. 2015. Reversed phase high-performance liquid chromatography-ultraviolet photodiode array detector validated simultaneous quantification of six bioactive phenolic acids in Roscoea purpurea tubers and their in-vitro cytotoxic potential against various cell lines. Pharma-cogn. Mag., 11(Suppl 3): S488.
  39. Kaur, G., et al. 2020. Isolation of lupenone (18-Lupen-3-one) from Roscoea purpurea root extract. Bangladesh J. Med. Sci., 19(4): 692.
  40. Kaur, G., et al. 2020. Isolation of catechins from Roscoea purpurea. J. Young Pharm., 12(4):389.
  41. Balkrishna, A., et al. 2020. Phytochemical botanical and biological paradigm of Astavarga plants, the ayurvedic rejuvenators. J. Nat. Ayurvedic Med., 2(145): 24.
  42. Sahu, M.S., et al. 2010. Evaluation of immuno-dulatory potential of ethanolic extract of Roscoea procera rhizomes in mice. J. Pharm. Bioallied Sci., 2(4): 346.
  43. Gopal, B.B., D.S. Shankar and R. Avishek. 2014. Study of antioxidant property of the rhizome extract Roscoea purpurea Sm. (kakoli) and its use in green synthesis of gold nanoparticles. Int. J. Res. Chem. Env., 4: 174-180.
  44. Joshi, P., et al. Comparative study of in-vitro antibacterial activity of essential oil of two Zingiber-aceae family species. Int. J. Res. Pharm. Pharm. Sci., 6 (2): 40-42.
  45. Rawat, S., et al. 2016. Genetic diversity analysis in natural populations of Roscoea procera Wall. from west Himalaya, India. Brazilian J. Bot., 39: 621-630.
  46. NBRI. Flagship programme: Threatened plants conservation. National Botanical Research Institute. Available at : https://nbri.res.in/threatened-plants-conservation.
  47. List of threatened wild medicinal plants of Himachal Pradesh. Available at: https://hpbiodiversity. gov.in/Pdf/Theratened%20wild%20medicinal%20 plants %of%20Himachal%20Pradesh.